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Structure-Activity Mechanism of Iron Oxide Nanozymes

Structure-Activity Mechanism of Iron Oxide Nanozymes

  • Ruofei Zhang
    Ruofei Zhang
    CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    R.Z. and H.Z. contributed equally to this work.
    More by Ruofei Zhang
  • Hanqing Zhao
    Hanqing Zhao
    CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100408, China
    R.Z. and H.Z. contributed equally to this work.
    More by Hanqing Zhao
  • , and 
  • Kelong Fan*
    Kelong Fan
    CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100408, China
    Nanozyme Medical Center, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450052, China
    *Email: [email protected]
    More by Kelong Fan
DOI: 10.1021/bk-2022-1422.ch001
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Publication Date (Web):October 19, 2022
Copyright © 2022 American Chemical Society. This publication is available under these Terms of Use.
Nanozymes: Design, Synthesis, and Applications
Chapter 1pp 1-35
ACS Symposium SeriesVol. 1422
ISBN13: 9780841297517eISBN: 9780841297500

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Abstract

The discovery of highly stable and low-cost nanozymes, nanomaterials with enzyme-like activity, opens a new portal for breaking through the application limitations of delicate natural enzymes. Iron oxide nanozymes, as one of the most representative nanozymes, were first discovered to exhibit enzyme-like activity, and were systematically and in-depth studied. Researches have found some structural factors that have an important impact on the catalytic activity. In this chapter, we introduce the enzyme-like activities of iron oxide nanozymes and systematically review the elucidated structure-activity relationships to gain insight into their enzyme-like catalytic mechanisms.

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